Murphy, who has two caps for Ireland to his name, will provide cover for the Manchester City goalkeeper. Given will start in goal in the match, which is the official opening of the Aviva Stadium in Dublin.
Murphy and his international teammates will have to wait to find out who will be in charge of the Republic side for the match as coach Giovanni Trapattoni was kept in hospital overnight after suspected food poisoning.
His illness did not prevent him naming the starting XI for Wednesday evening's game, with Given unsurprisingly given the nod ahead of Murphy.
The Italian coach is not the only fitness doubt for the match, with Celtic's Cillian Sheridan on standby to play should the Wolves forward Kevin Doyle not recover from a leg muscle problem.
Liam Lawrence has had to pull out of the squad with a groin strain. Keith Fahey, the Birmingham City forward, will take his place in the starting XI.
Starting XI to face Argentina (7.45pm, Sky Sports 1): Given (Manchester City); McShane (Hull City), Dunne (Aston Villa), O'Shea (Manchester United), Kilbane (Hull City); Fahey (Birmingham City), Andrews (Blackburn Rovers), Green (Derby County), Duff (Fulham); Keane (Tottenham Hotspur), Doyle (Wolves)/Sheridan (Celtic).